Dynamically evolving novel overlapping gene as a factor in the SARS-CoV-2 pandemic

Understanding the emergence of novel viruses requires an accurate and comprehensive annotation of their genomes. Overlapping genes (OLGs) are common in viruses and have been associated with pandemics but are still widely overlooked. We identify and characterize ORF3d, a novel OLG in SARS-CoV-2 that...

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Udgivet i:eLife
Main Authors: Nelson, Chase W, Ardern, Zachary, Goldberg, Tony L, Meng, Chen, Kuo, Chen-Hao, Ludwig, Christina, Kolokotronis, Sergios-Orestis, Wei, Xinzhu
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2020
Fag:
Evolutionary Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7655111/
https://ncbi.nlm.nih.gov/pubmed/33001029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.59633
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