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OLGenie: Estimating Natural Selection to Predict Functional Overlapping Genes
Purifying (negative) natural selection is a hallmark of functional biological sequences, and can be detected in protein-coding genes using the ratio of nonsynonymous to synonymous substitutions per site (d(N)/d(S)). However, when two genes overlap the same nucleotide sites in different frames, synon...
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| Publicado no: | Mol Biol Evol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7531306/ https://ncbi.nlm.nih.gov/pubmed/32243542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msaa087 |
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