The ACE2-binding interface of SARS-CoV-2 Spike inherently deflects immune recognition

The COVID-19 pandemic remains a global threat, and host immunity remains the main mechanism of protection against the disease. The spike protein on the surface of SARS-CoV-2 is a major antigen and its engagement with human ACE2 receptor plays an essential role in viral entry into host cells. Consequ...

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Pubblicato in:bioRxiv
Autori principali: Hattori, Takamitsu, Koide, Akiko, Panchenko, Tatyana, Romero, Larizbeth A., Teng, Kai Wen, Tada, Takuya, Landau, Nathaniel R., Koide, Shohei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7654858/
https://ncbi.nlm.nih.gov/pubmed/33173869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.11.03.365270
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