Acetaldehyde suppresses HBV-MHC class I complex presentation on hepatocytes via induction of ER stress and Golgi fragmentation

Alcohol consumption worsens hepatitis B virus (HBV) infection pathogenesis. We have recently reported that acetaldehyde suppressed HBV peptide-major histocompatibility complex I (MHC class I) complex display on hepatocytes, limiting recognition and subsequent removal of the infected hepatocytes by H...

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Pubblicato in:Am J Physiol Gastrointest Liver Physiol
Autori principali: Ganesan, Murali, Mathews, Saumi, Makarov, Edward, Petrosyan, Armen, Kharbanda, Kusum K., Kidambi, Srivatsan, Poluektova, Larisa Y., Casey, Carol A., Osna, Natalia A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7654643/
https://ncbi.nlm.nih.gov/pubmed/32755306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00109.2020
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