Lower gefitinib dose led to earlier resistance acquisition before emergence of T790M mutation in epidermal growth factor receptor‐mutated lung cancer model

Non‐small‐cell lung cancers with epidermal growth factor receptor (EGFR) mutations are sensitive to EGFR tyrosine kinase inhibitors (TKIs); however, unlike cytotoxic agents, it is generally accepted that minimal doses of drugs inhibiting target molecules are sufficient when molecular‐targeted agents...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Sci
Egile Nagusiak: Hayakawa, Hiromi, Ichihara, Eiki, Ohashi, Kadoaki, Ninomiya, Takashi, Yasugi, Masayuki, Takata, Saburo, Sakai, Katsuya, Matsumoto, Kunio, Takigawa, Nagio, Tanimoto, Mitsune, Kiura, Katsuyuki
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2013
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7654246/
https://ncbi.nlm.nih.gov/pubmed/24033722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12284
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