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A Broad Substrate Scope of Aza-Friedel-Crafts Alkylation for the Synthesis of Quaternary α-Amino Esters

A versatile synthetic protocol of aza-Friedel-Crafts alkylation has been developed for the synthesis of quaternary α-amino esters. This operationally simple alkylation proceeds under ambient conditions with high efficiency, regioselectivity, and an exceptionally broad scope of arene nucleophiles. A...

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Bibliografske podrobnosti
izdano v:Org Lett
Main Authors: Zhao, Guangkuan, Samanta, Shyam S., Michieletto, Jessica, Roche, Stéphane P.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7654210/
https://ncbi.nlm.nih.gov/pubmed/32649206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.0c01895
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