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CRISPR/Cas9 as an antiviral against Orthopoxviruses using an AAV vector

A vaccine for smallpox is no longer administered to the general public, and there is no proven, safe treatment specific to poxvirus infections, leaving people susceptible to infections by smallpox and other zoonotic Orthopoxviruses such as monkeypox. Using vaccinia virus (VACV) as a model organism f...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Siegrist, Cathryn M., Kinahan, Sean M., Settecerri, Taylor, Greene, Adrienne C., Santarpia, Joshua L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653928/
https://ncbi.nlm.nih.gov/pubmed/33168908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76449-9
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