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CRISPR/Cas9 as an antiviral against Orthopoxviruses using an AAV vector

A vaccine for smallpox is no longer administered to the general public, and there is no proven, safe treatment specific to poxvirus infections, leaving people susceptible to infections by smallpox and other zoonotic Orthopoxviruses such as monkeypox. Using vaccinia virus (VACV) as a model organism f...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Siegrist, Cathryn M., Kinahan, Sean M., Settecerri, Taylor, Greene, Adrienne C., Santarpia, Joshua L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653928/
https://ncbi.nlm.nih.gov/pubmed/33168908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76449-9
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