Cellular and molecular outcomes of glutamine supplementation in the brain of succinic semialdehyde dehydrogenase‐deficient mice

Succinic semialdehyde dehydrogenase deficiency (SSADHD) manifests with low levels of glutamine in the brain, suggesting that central glutamine deficiency contributes to pathogenesis. Recently, we attempted to rescue the disease phenotype of aldh5a1 (−/−) mice, a murine model of SSADHD with dietary g...

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Detaylı Bibliyografya
Yayımlandı:JIMD Rep
Asıl Yazarlar: Brown, Madalyn N., Gibson, K. Michael, Schmidt, Michelle A., Walters, Dana C., Arning, Erland, Bottiglieri, Teodoro, Roullet, Jean‐Baptiste
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley & Sons, Inc. 2020
Konular:
Research Reports
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653255/
https://ncbi.nlm.nih.gov/pubmed/33204597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmd2.12151
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