HIF‐1α ameliorates tubular injury in diabetic nephropathy via HO‐1–mediated control of mitochondrial dynamics

OBJECTIVES: In diabetic nephropathy (DN), hypoxia‐inducible factor‐1α (HIF‐1α) activation in tubular cells plays an important protective role against kidney injury. The effects may occur via the target genes of HIF‐1α, such as haem oxygenase‐1 (HO‐1), but the exact mechanisms are incompletely unders...

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Bibliografiske detaljer
Udgivet i:Cell Prolif
Main Authors: Jiang, Na, Zhao, Hao, Han, Yachun, Li, Li, Xiong, Shan, Zeng, Lingfeng, Xiao, Ying, Wei, Ling, Xiong, Xiaofen, Gao, Peng, Yang, Ming, Liu, Yu, Sun, Lin
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653251/
https://ncbi.nlm.nih.gov/pubmed/32975326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12909
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