SMO mutations confer poor prognosis in malignant pleural mesothelioma

BACKGROUND: Malignant pleural mesothelioma (MPM) is an aggressive tumor but approximately 12% of patients survive more than 3 years. The biological differences underlying better outcomes are not known. Several targeted agents and immunotherapy have been ineffective. Hedgehog (Hh) is one emerging pat...

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Bibliographic Details
Published in:Transl Lung Cancer Res
Main Authors: Signorelli, Diego, Proto, Claudia, Botta, Laura, Trama, Annalisa, Tiseo, Marcello, Pasello, Giulia, Lo Russo, Giuseppe, Fabbri, Alessandra, Imbimbo, Martina, Busico, Adele, Prelaj, Arsela, Ferrara, Roberto, Galli, Giulia, De Toma, Alessandro, Tamborini, Elena, Pastorino, Ugo, de Braud, Filippo, Gatta, Gemma, Garassino, Marina Chiara, Ganzinelli, Monica
Format: Artigo
Language:Inglês
Published: AME Publishing Company 2020
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653142/
https://ncbi.nlm.nih.gov/pubmed/33209614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tlcr-19-425
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