Concomitant EML4-ALK rearrangement and EGFR mutation in non-small cell lung cancer patients: a literature review of 100 cases

The discovery of EGFR mutations and EML4-ALK gene rearrangements has radically changed the therapeutic scenario for patients with advanced non-small cell lung cancer. ALK and EGFR tyrosine-kinase inhibitors showed better activity and efficacy than standard chemotherapy in the first and second line t...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Lo Russo, Giuseppe, Imbimbo, Martina, Corrao, Giulia, Proto, Claudia, Signorelli, Diego, Vitali, Milena, Ganzinelli, Monica, Botta, Laura, Zilembo, Nicoletta, de Braud, Filippo, Garassino, Marina Chiara
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601787/
https://ncbi.nlm.nih.gov/pubmed/28938691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17431
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