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ZAP-70 Shapes the Immune Microenvironment in B Cell Malignancies
Zeta-chain-associated protein kinase-70 (ZAP-70) is a tyrosine kinase mainly expressed in T cells, NK cells and a subset of B cells. Primarily it functions in T cell receptor (TCR) activation through its tyrosine kinase activity. Aberrant expression of ZAP-70 has been evidenced in different B cell m...
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| Udgivet i: | Front Oncol |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7653097/ https://ncbi.nlm.nih.gov/pubmed/33194762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.595832 |
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