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Somatic copy number gains in MYC, BCL2, and BCL6 identifies a subset of aggressive alternative-DH/TH DLBCL patients

Double/triple hit lymphoma (DH/TH), known as high-grade B-cell lymphoma (HGBL), is an aggressive diffuse large B cell lymphoma (DLBCL), defined as having concurrent MYC, BCL2, and/or BCL6 gene rearrangements. While gene rearrangements represent significant genetic events in cancer, copy number alter...

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Detalhes bibliográficos
Publicado no:Blood Cancer J
Main Authors: Krull, Jordan E., Wenzl, Kerstin, Hartert, Keenan T., Manske, Michelle K., Sarangi, Vivekananda, Maurer, Matthew J., Larson, Melissa C., Nowakowski, Grzegorz S., Ansell, Stephen M., McPhail, Ellen, Habermann, Thomas M., Link, Brian K., King, Rebecca L., Cerhan, James R., Novak, Anne J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7652824/
https://ncbi.nlm.nih.gov/pubmed/33168821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41408-020-00382-3
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