Somatic copy number gains in MYC, BCL2, and BCL6 identifies a subset of aggressive alternative-DH/TH DLBCL patients

Double/triple hit lymphoma (DH/TH), known as high-grade B-cell lymphoma (HGBL), is an aggressive diffuse large B cell lymphoma (DLBCL), defined as having concurrent MYC, BCL2, and/or BCL6 gene rearrangements. While gene rearrangements represent significant genetic events in cancer, copy number alter...

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Bibliografske podrobnosti
izdano v:Blood Cancer J
Main Authors: Krull, Jordan E., Wenzl, Kerstin, Hartert, Keenan T., Manske, Michelle K., Sarangi, Vivekananda, Maurer, Matthew J., Larson, Melissa C., Nowakowski, Grzegorz S., Ansell, Stephen M., McPhail, Ellen, Habermann, Thomas M., Link, Brian K., King, Rebecca L., Cerhan, James R., Novak, Anne J.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7652824/
https://ncbi.nlm.nih.gov/pubmed/33168821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41408-020-00382-3
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