Oral Methioninase Inhibits Recurrence in a PDOX Mouse Model of Aggressive Triple-negative Breast Cancer

Background/Aim: The aim of the study was to use a triple-negative breast cancer (TNBC) patient-derived orthotopic xenograft (PDOX) model to examine the efficacy of oral recombinant methioninase (o-rMETase) against this recalcitrant disease. Materials and Methods: The TNBC tumor from a patient was im...

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Publicat a:In Vivo
Autors principals: LIM, HYE IN, HAMADA, KAZUYUKI, YAMAMOTO, JUN, HAN, QINHONG, TAN, YUYING, JUN CHOI, HEE, NAM, SEOK JIN, BOUVET, MICHAEL, HOFFMAN, ROBERT M.
Format: Artigo
Idioma:Inglês
Publicat: International Institute of Anticancer Research 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7652477/
https://ncbi.nlm.nih.gov/pubmed/32871751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/invivo.12039
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