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Homoharringtonine Exerts an Antimyeloma Effect by Promoting Excess Parkin-Dependent Mitophagy

PURPOSE: Homoharringtonine (HHT) has been used as an antileukemia agent in the clinic which processes a high-potential therapeutic efficacy against multiple myeloma (MM). In this study, we investigated the antimyeloma mechanism of HHT. METHODS: Three MM cell lines and a xenograft model were applied....

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Zhang, Yanyu, Huang, Ning, Xu, Jie, Zheng, Wei, Cui, Xing
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7652225/
https://ncbi.nlm.nih.gov/pubmed/33177810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S279054
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