CTNI-33. DEBIO1347, AN ORAL FGFR INHIBITOR: RESULTS FROM A SINGLE CENTER STUDY IN PEDIATRIC PATIENTS WITH RECURRENT/REFRACTORY FGFR ALTERED GLIOMAS

BACKGROUND: Oncogenic driver alterations in fibroblast growth factor receptors (FGFRs) are present in a subset of pediatric gliomas. Debio1347 is an orally available, highly selective FGFR 1–3 inhibitor with a favorable safety profile and encouraging preliminary clinical activity in an adult phase 1...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Farouk Sait, Sameer, Rosenblum, Marc, Bale, Tejus, Haque, Sofia, Gilheeney, Stephen, Spatz, Krisoula, Prince, Daniel, Ibanez, Katarzyna, Dunkel, Ira, Karajannis, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Clinical Trials: Non-Immunologic
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651617/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.200
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