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EXTH-32. TARGETED STAT3 INHIBITION IMPAIRS MDSC MOBILIZATION AND RECRUITMENT IN GLIOBLASTOMA
BACKGROUND: Glioblastoma tumors (GBM) are comprised upwards of 30 percent by glioma-associated myeloid cells (GAMs). A large fraction of GAMs are myeloid-derived suppressor cells (MDSC) thought to traffic in from peripheral circulation. MDSCs foster a hospitable environment for cancer cells by regul...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7651582/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.386 |
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