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EXTH-32. TARGETED STAT3 INHIBITION IMPAIRS MDSC MOBILIZATION AND RECRUITMENT IN GLIOBLASTOMA

BACKGROUND: Glioblastoma tumors (GBM) are comprised upwards of 30 percent by glioma-associated myeloid cells (GAMs). A large fraction of GAMs are myeloid-derived suppressor cells (MDSC) thought to traffic in from peripheral circulation. MDSCs foster a hospitable environment for cancer cells by regul...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuro Oncol
Prif Awduron: von Roemeling, Christina, Li, Chenglong, Mitchell, Duane
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651582/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.386
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