DDRE-05. DECREASED EXPRESSION OF DNA DAMAGE RESPONSE PATHWAYS CORRELATES WITH SYNERGISTIC ACTIVITY OF TEMOZOLOMIDE WITH ATR INHIBITORS IN GLIOBLASTOMA

The lack of knowledge about the relationship between tumor genotypes and therapeutic responses remains one of the most important gaps in enabling the development of effective targeted cancer therapies. Increasing evidence supports the notion that DNA damage response (DDR) signaling plays an importan...

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Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Wu, Shaofang, Li, Xiaolong, Singh, Sanjay, Koul, Dimpy, Yung, W K Alfred
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Drug Discovery, Drug Resistance
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651512/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.250
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