TAMI-57. MEDULLOBLASTOMA UTILIZE GABA TRANSAMINASE TO SURVIVE IN THE CEREBROSPINAL FLUID MICROENVIRONMENT AND PROMOTE LEPTOMENINGEAL DISSEMINATION

Medulloblastoma (MB) is a malignant pediatric brain tumor. Studies have shown heterogeneous cells amongst the tumor bulk which mirror normal neural cells in various neurodevelopmental stages. To discern exploited mechanisms promoting MB leptomeningeal disease, we drew conclusions from developmental...

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Main Authors: Martirosian, Vahan, Deshpande, Krutika, Zhou, Hao, Shen, Keyue, Stepanosyan, Vazgen, Remsik, Jan, Boire, Adrienne, Isakov, Danielle, De Feyter, Henk, Hurth, Kyle, Nakamura, Brooke, Shao, Ling, Northcott, Paul, Wiemels, Joe, Li, Shaobo, Neman, Josh
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
Assuntos:
Tumor Microenvironment/Angiogenesis/Metabolism/Invasion
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651415/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.944
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