TAMI-57. MEDULLOBLASTOMA UTILIZE GABA TRANSAMINASE TO SURVIVE IN THE CEREBROSPINAL FLUID MICROENVIRONMENT AND PROMOTE LEPTOMENINGEAL DISSEMINATION

Medulloblastoma (MB) is a malignant pediatric brain tumor. Studies have shown heterogeneous cells amongst the tumor bulk which mirror normal neural cells in various neurodevelopmental stages. To discern exploited mechanisms promoting MB leptomeningeal disease, we drew conclusions from developmental...

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Vydáno v:Neuro Oncol
Hlavní autoři: Martirosian, Vahan, Deshpande, Krutika, Zhou, Hao, Shen, Keyue, Stepanosyan, Vazgen, Remsik, Jan, Boire, Adrienne, Isakov, Danielle, De Feyter, Henk, Hurth, Kyle, Nakamura, Brooke, Shao, Ling, Northcott, Paul, Wiemels, Joe, Li, Shaobo, Neman, Josh
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Tumor Microenvironment/Angiogenesis/Metabolism/Invasion
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651415/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.944
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