NCMP-27. THE USE OF INTRAVENOUS IMMUNOGLOBULIN (IVIG) DURING SEVERE NEUROTOXICITY AMONG THE RECIPIENTS OF CHIMERIC ANTIGEN RECEPTOR T-CELLS (CAR-T) THERAPY

INTRODUCTION: Severe Immune effector Cell-Associated Neurotoxicity Syndrome (ICANS) occurs in ~ 30% of Diffuse Large B Cell Lymphoma (DLBCL) patients treated with CAR-T cell therapy. The current treatment for severe ICANS is glucocorticoids, and this may be combined with tocilizumab for concurrent c...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Mokhtari, Sepideh, Asquith, Justin, Bachmeier, Christina, Faramand, Rawan, Kim, Youngchul, Peguero, Edwin, Sahebjam, Solmaz, Jain, Michael, Vogelbaum, Michael, Davila, Marco, Forsyth, Peter, Locke, Frederick, Aleksandr, Lazaryan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Neurological Complications of Cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651408/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.538
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