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Mechanisms and Management of Chimeric Antigen Receptor T-Cell Therapy Related Toxicities

Chimeric antigen receptor T-cell (CAR-T) therapy has proven to be a very effective cancer immunotherapy. Axicabtagene ciloleucel and Tisagenlecleucel are the first in class anti-CD19 CAR-T-cells currently available for relapsed-refractory adult large B-cell lymphoma. Tisagenlecleucel is also availab...

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Detalhes bibliográficos
Publicado no:BioDrugs
Main Authors: Dholaria, Bhagirathbhai R., Bachmeier, Christina, Locke, Frederick
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733400/
https://ncbi.nlm.nih.gov/pubmed/30560413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40259-018-0324-z
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