RTID-03. A PHASE I CLINICAL TRIAL TO EVALUATE MTD OF PERAMPANEL AND MEMANTINE IN COMBINATION WITH STANDARD CHEMORADIOTHERAPY FOR THE TREATMENT OF PATIENTS WITH NEWLY DIAGNOSED GBM –A STUDY DESIGN

BACKGROUND: Glioblastoma (GBM) is the most aggressive malignant brain tumor in adults with poor prognosis. Effective treatment is urgently needed. Recent studies demonstrated cross-talk between neuron and glioma through neuro-transmitter glutamate receptors (AMPA and NMDA receptors) promotes glioma...

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Bibliographische Detailangaben
Veröffentlicht in:Neuro Oncol
Hauptverfasser: Kong, Xiao-Tang, Albala, Bruce, Du, Senxi, Hrachova, Maya, Bota, Daniela
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Randomized Trials in Development
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651373/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.808
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