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RTID-03. A PHASE I CLINICAL TRIAL TO EVALUATE MTD OF PERAMPANEL AND MEMANTINE IN COMBINATION WITH STANDARD CHEMORADIOTHERAPY FOR THE TREATMENT OF PATIENTS WITH NEWLY DIAGNOSED GBM –A STUDY DESIGN

BACKGROUND: Glioblastoma (GBM) is the most aggressive malignant brain tumor in adults with poor prognosis. Effective treatment is urgently needed. Recent studies demonstrated cross-talk between neuron and glioma through neuro-transmitter glutamate receptors (AMPA and NMDA receptors) promotes glioma...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Kong, Xiao-Tang, Albala, Bruce, Du, Senxi, Hrachova, Maya, Bota, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651373/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.808
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