NCMP-24. PRE-INFUSION NEUROFILAMENT LIGHT CHAIN (NFL) LEVELS PREDICT THE DEVELOPMENT OF IMMUNE EFFECTOR CELL-ASSOCIATED NEUROTOXICITY SYNDROME (ICANS)

Neurological side effects after chimeric antigen receptor-modified (CAR) T cell therapy are common and potentially devastating. Termed immune effector cell-associated neurotoxicity syndrome (ICANS), symptoms range from mild encephalopathy to diffuse cerebral edema. No predictive biomarkers exist to...

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Vydáno v:Neuro Oncol
Hlavní autoři: Butt, Omar, Zhou, Alice, Schindler, Suzanne, Fagan, Anne, Dipersio, John, Ghobadi, Armin, Ances, Beau
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Neurological Complications of Cancer
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651371/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.535
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