IMMU-21. THE COMBINATION OF DELTA-24-ACT WITH AN IMMUNE CHECKPOINT INHIBITOR RESULTS IN ANTI-GLIOMA EFFECT AND IMMUNE MEMORY

Oncolytic viruses have become promising therapeutic candidates to treat gliomas. Our group has developed Delta-24-ACT, an oncolytic adenovirus armed with the positive costimulatory ligand 4-1BBL which is capable to trigger the activation of T cells and thereby increase their antitumor immune respons...

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Vydáno v:Neuro Oncol
Hlavní autoři: Puigdelloses, Montserrat, Laspidea, Virginia, Garcia-Moure, Marc, De la Nava, Daniel, Hambardzumyan, Dolores, Chen, Zhihong, Labiano, Sara, Fueyo, Juan, Gomez-Manzano, Candelaria, de Larraya, Jaime Gállego-pérez, M Alonso, Marta
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651344/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.451
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