IMMU-01. THE ONCOLYTIC VIRUS DELTA-24-RGD IN COMBINATION WITH AN AGONISTIC CD40 MAB INDUCES A DURABLE AND SYNERGISTIC ANTI-TUMOR IMMUNE EFFECT IN DIPG PRECLINICAL MODELS

With a 2-year survival less than 20%, Diffuse Intrinsic Pontine Glioma (DIPG) is the principal cause of pediatric death. Despite recent advances in the current treatments, the outcome for children with DIPGs remains dismal. Since the approval of T-VEC for melanoma by the FDA, oncolytic adenoviruses...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Labiano, Sara, Laspidea, Virginia, Garcia-Moure, Marc, Puigdelloses, Montserrat, Becher, Oren J, Gomez-Manzano, Candelaria, Fueyo, Juan, Patiño-Garcia, Ana, Alonso, Marta M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Immunology/Immunotherapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168238/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noab090.109
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