EXTH-08. MINIPIG MODELS OF NEUROFIBROMATOSIS TYPE 1 FOR THERAPEUTIC DEVELOPMENT

Neurofibromatosis Type 1 (NF1) is a genetic disease caused by mutations in the neurofibromin 1 (NF1) gene. NF1 patients present with a variety of clinical manifestations and are predisposed to cancer development. Many NF1 animal models have been developed, yet none display the spectrum of disease se...

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Publicado en:Neuro Oncol
Autores principales: Watson, Adrienne, Osum, Sara, Taisto, Mandy, Tschida, Barbara, Duerre, Dylan, Moertel, Christopher, Kirstein, Mark, Largaespada, David, Oribamise, Eunice
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2020
Materias:
Preclinical Experimental Therapeutics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651277/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.362
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