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EXTH-40. THERAPEUTICALLY TARGETING DE NOVO PURINE BIOSYNTHESIS IN DIFFUSE INTRINSIC PONTINE GLIOMA

Diffuse intrinsic pontine glioma (DIPG) is an incurable brainstem malignancy in children with median survival less than 1 year and 5-year overall survival only 2 percent. Little progress has been made in treating this deadly disease due to its inoperable location and treatments aimed at targets defi...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Mersich, Ian, Dasgupta, Biplab
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651155/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.394
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