TMOD-12. ESTABLISHING A CLINICALLY RELEVANT MODEL OF MESENCHYMAL GLIOBLASTOMA (GBM) TO STUDY RESPONSE TO STANDARD OF CARE TREATMENT AND IMMUNE CHECKPOINT INHIBITION (ICI).

GBM is a devastating disease with peak incidence in the seventh decade. Pre-clinical models are essential for studying resistance mechanisms and screening novel therapies. However, historically these models have failed to predict response in humans. Current models seldom incorporate surgical resecti...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Clerkin, James, Connor, Kate, Sweeney, Kieron, White, Kieron, Shiels, Liam, Maher, Stephen, Marignol, Laure, Prehn, Jochen H M, O’Brien, David, Byrne, Annette
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Tumor Models
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651026/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.963
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