PATH-28. EXTENT AND PROGNOSTIC VALUE OF MGMT PROMOTOR METHYLATION DEPEND ON IDH MUTATION AND 1p19q CO-DELETION IN GLIOMA WHO GRADE II

INTRODUCTION: Methylation of the promotor region of the O6-methylguanin-DNA-methyltransferase (MGMT) gene is associated with increased survival in low- and high-grade glioma. It is unknown whether this association also applies to the 2016 WHO categories of glioma WHO grade II. MATERIAL AND METHODS:...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Karschnia, Philipp, Teske, Nico, Siller, Sebastian, Dorostkar, Mario M, Weller, Jonathan, Herms, Jochen, Baehring, Joachim M, von Baumgarten, Louisa, Tonn, Joerg-Christian, Thon, Niklas
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Molecular Pathology & Classification
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651020/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.709
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