TAMI-39. AGE-DEPENDENT PHENOTYPIC CONVERSION FROM NEURONAL ACTIVITY TO NEURO-INFLAMMATION IN GLIOBLASTOMA PROGRESSION

The rise in population aging worldwide is causing an unparalleled increase in death from many cancers, including glioblastoma (GBM). Here, we have explored the impact of aging and rejuvenation on GBM tumorigenesis. Compared with neuro-inflammatory old GBM, young GBM displayed elevated neuronal/synap...

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Библиографические подробности
Опубликовано в: :Neuro Oncol
Главные авторы: Yamashita, Daisuke, Flanary, Victoria, Munk, Rachel, Sonomura, Kazuhiro, Ozaki, Saya, Kawaguchi, Riki, Suehiro, Satoshi, Ghosh, Sadashib, Chen, Zhihong, Yamaguchi, Shinobu, Komarova, Svetlana, Bastola, Soniya, Bernstock, Joshua, King, Gwendalyn, Kunieda, Dr, Hambardzumyan, Dolores, Kondo, Toru, Kornblum, Harley, Crossman, David, Hackney, James, Horvath, Steve, Sato, Taka-aki, Gorospe, Myriam, Nakano, Ichiro
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2020
Предметы:
Tumor Microenvironment/Angiogenesis/Metabolism/Invasion
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650979/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.927
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