TAMI-39. AGE-DEPENDENT PHENOTYPIC CONVERSION FROM NEURONAL ACTIVITY TO NEURO-INFLAMMATION IN GLIOBLASTOMA PROGRESSION

The rise in population aging worldwide is causing an unparalleled increase in death from many cancers, including glioblastoma (GBM). Here, we have explored the impact of aging and rejuvenation on GBM tumorigenesis. Compared with neuro-inflammatory old GBM, young GBM displayed elevated neuronal/synap...

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Vydáno v:Neuro Oncol
Hlavní autoři: Yamashita, Daisuke, Flanary, Victoria, Munk, Rachel, Sonomura, Kazuhiro, Ozaki, Saya, Kawaguchi, Riki, Suehiro, Satoshi, Ghosh, Sadashib, Chen, Zhihong, Yamaguchi, Shinobu, Komarova, Svetlana, Bastola, Soniya, Bernstock, Joshua, King, Gwendalyn, Kunieda, Dr, Hambardzumyan, Dolores, Kondo, Toru, Kornblum, Harley, Crossman, David, Hackney, James, Horvath, Steve, Sato, Taka-aki, Gorospe, Myriam, Nakano, Ichiro
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Tumor Microenvironment/Angiogenesis/Metabolism/Invasion
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650979/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.927
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