CTIM-32. PHASE II AND BIOMARKER STUDY OF PEMBROLIZUMAB OR PEMBROLIZUMAB PLUS BEVACIZUMAB FOR RECURRENT GLIOBLASTOMA PATIENTS

PURPOSE: Vascular endothelial growth factor (VEGF) is upregulated in glioblastoma and may contribute to immunosuppression. We performed a phase 2 study of pembrolizumab, a programmed death-1 (PD-1) blocking antibody alone or with the anti-VEGF antibody bevacizumab in recurrent glioblastoma with deta...

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Podrobná bibliografie
Vydáno v:Neuro Oncol
Hlavní autoři: Reardon, David, Molinaro, Annette, Peters, Katherine, Clarke, Jennifer, Jordan, Justin, de Groot, John, Nghiemphu, Phioanh, Kaley, Thomas, Colman, Howard, McCluskey, Christine, Smith, Timothy, Cote, David, Severgnini, Mariano, Yearley, Jennifer, Zhao, Qing, Blumenschein, Wendy, Duda, Gabriel, Muzikansky, Alona, Jain, Rakesh, Wen, Patrick, Nayak, Lakshmi
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Clinical Trials: Immunologic
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650927/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.166
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