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In Silico Model for Chemical-Induced Chromosomal Damages Elucidates Mode of Action and Irrelevant Positives

In silico tools to predict genotoxicity have become important for high-throughput screening of chemical substances. However, current in silico tools to evaluate chromosomal damage do not discriminate in vitro-specific positives that can be followed by in vivo tests. Herein, we establish an in silico...

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Détails bibliographiques
Publié dans:Genes (Basel)
Auteurs principaux: Fujita, Yurika, Morita, Osamu, Honda, Hiroshi
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650694/
https://ncbi.nlm.nih.gov/pubmed/33050664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11101181
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