Targeting Vesicular LGALS3BP by an Antibody-Drug Conjugate as Novel Therapeutic Strategy for Neuroblastoma

SIMPLE SUMMARY: Antibody Drug Conjugates are an emerging class of biopharmaceuticals that have seen an impressive increase of attention in the field of cancer therapy. Here, we describe the therapeutic activity of 1959-sss/DM3, a non-internalizing ADC targeting LGALS3BP, a secreted, extracellular ve...

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書誌詳細
出版年:Cancers (Basel)
主要な著者: Capone, Emily, Lamolinara, Alessia, Pastorino, Fabio, Gentile, Roberta, Ponziani, Sara, Di Vittorio, Giulia, D’Agostino, Daniela, Bibbò, Sandra, Rossi, Cosmo, Piccolo, Enza, Iacobelli, Valentina, Lattanzio, Rossano, Panella, Valeria, Sallese, Michele, De Laurenzi, Vincenzo, Giansanti, Francesco, Sala, Arturo, Iezzi, Manuela, Ponzoni, Mirco, Ippoliti, Rodolfo, Iacobelli, Stefano, Sala, Gianluca
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2020
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Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650653/
https://ncbi.nlm.nih.gov/pubmed/33076448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12102989
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