Targeting Vesicular LGALS3BP by an Antibody-Drug Conjugate as Novel Therapeutic Strategy for Neuroblastoma

SIMPLE SUMMARY: Antibody Drug Conjugates are an emerging class of biopharmaceuticals that have seen an impressive increase of attention in the field of cancer therapy. Here, we describe the therapeutic activity of 1959-sss/DM3, a non-internalizing ADC targeting LGALS3BP, a secreted, extracellular ve...

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Bibliografski detalji
Izdano u:Cancers (Basel)
Glavni autori: Capone, Emily, Lamolinara, Alessia, Pastorino, Fabio, Gentile, Roberta, Ponziani, Sara, Di Vittorio, Giulia, D’Agostino, Daniela, Bibbò, Sandra, Rossi, Cosmo, Piccolo, Enza, Iacobelli, Valentina, Lattanzio, Rossano, Panella, Valeria, Sallese, Michele, De Laurenzi, Vincenzo, Giansanti, Francesco, Sala, Arturo, Iezzi, Manuela, Ponzoni, Mirco, Ippoliti, Rodolfo, Iacobelli, Stefano, Sala, Gianluca
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650653/
https://ncbi.nlm.nih.gov/pubmed/33076448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12102989
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