Targeting Vesicular LGALS3BP by an Antibody-Drug Conjugate as Novel Therapeutic Strategy for Neuroblastoma

SIMPLE SUMMARY: Antibody Drug Conjugates are an emerging class of biopharmaceuticals that have seen an impressive increase of attention in the field of cancer therapy. Here, we describe the therapeutic activity of 1959-sss/DM3, a non-internalizing ADC targeting LGALS3BP, a secreted, extracellular ve...

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Xehetasun bibliografikoak
Argitaratua izan da:Cancers (Basel)
Egile Nagusiak: Capone, Emily, Lamolinara, Alessia, Pastorino, Fabio, Gentile, Roberta, Ponziani, Sara, Di Vittorio, Giulia, D’Agostino, Daniela, Bibbò, Sandra, Rossi, Cosmo, Piccolo, Enza, Iacobelli, Valentina, Lattanzio, Rossano, Panella, Valeria, Sallese, Michele, De Laurenzi, Vincenzo, Giansanti, Francesco, Sala, Arturo, Iezzi, Manuela, Ponzoni, Mirco, Ippoliti, Rodolfo, Iacobelli, Stefano, Sala, Gianluca
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650653/
https://ncbi.nlm.nih.gov/pubmed/33076448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12102989
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