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Aberrantly Expressed RECQL4 Helicase Supports Proliferation and Drug Resistance of Human Glioma Cells and Glioma Stem Cells

SIMPLE SUMMARY: Human RecQ helicases participate in DNA replication, repair and transcription. Due to important roles in many cellular processes, deregulation of these helicases in cancer could be tumour promoting. We found upregulated RECQL4 expression in highly malignant brain tumours (glioblastom...

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Publicat a:Cancers (Basel)
Autors principals: Król, Sylwia K., Kaczmarczyk, Agnieszka, Wojnicki, Kamil, Wojtas, Bartosz, Gielniewski, Bartłomiej, Grajkowska, Wieslawa, Kotulska, Katarzyna, Szczylik, Cezary, Czepko, Ryszard, Banach, Mariusz, Kaspera, Wojciech, Szopa, Wojciech, Marchel, Andrzej, Czernicki, Tomasz, Kaminska, Bozena
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650617/
https://ncbi.nlm.nih.gov/pubmed/33050631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12102919
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