Aberrantly Expressed RECQL4 Helicase Supports Proliferation and Drug Resistance of Human Glioma Cells and Glioma Stem Cells

SIMPLE SUMMARY: Human RecQ helicases participate in DNA replication, repair and transcription. Due to important roles in many cellular processes, deregulation of these helicases in cancer could be tumour promoting. We found upregulated RECQL4 expression in highly malignant brain tumours (glioblastom...

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Publicado no:Cancers (Basel)
Main Authors: Król, Sylwia K., Kaczmarczyk, Agnieszka, Wojnicki, Kamil, Wojtas, Bartosz, Gielniewski, Bartłomiej, Grajkowska, Wieslawa, Kotulska, Katarzyna, Szczylik, Cezary, Czepko, Ryszard, Banach, Mariusz, Kaspera, Wojciech, Szopa, Wojciech, Marchel, Andrzej, Czernicki, Tomasz, Kaminska, Bozena
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650617/
https://ncbi.nlm.nih.gov/pubmed/33050631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12102919
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