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BIOM-28. IDENTIFICATION OF SOLUBLE AXL AS A POTENTIAL NON-INVASIVE SERUM BIOMARKER FOR GLIOBLASTOMA

AXL, a member of the TAM family of tyrosine kinases, engages cellular pathways that promote a cancer phenotype. In glioblastoma, increasing AXL expression is associated with worse prognosis. The extracellular domain of AXL is cleaved by the sheddases ADAM10 and ADAM17, releasing soluble AXL (sAXL),...

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書誌詳細
出版年:Neuro Oncol
主要な著者: Akhtar, Parvez, Raymond, Daniel, Fukui, Melanie, Zwernik, Samuel, Winn, Robert, LaCrosse, Amber, Last, Brittany, Polinske, Natalie, Rovin, Richard
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650491/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.028
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