BIOM-57. PEDIATRIC TUMOR CLASSIFICATION THROUGH GENOME-WIDE METHYLATION PROFILING OF EXTRACELLULAR VESICLE DNA

BACKGROUND: Genome-wide methylation profiling reliably classifies pediatric central nervous system (CNS) tumors. Extracellular vesicles (EVs) are released by pediatric CNS tumor cells (pCC) and contain high molecular weight tumor DNA, rendering EVs a potential biomarker source to identify tumor subg...

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Autores principales: Ricklefs, Franz, Maire, Cecile, Fita, Krys, Fritzsche, Friederike, Kammler, Gertrud, Westphal, Manfred, Lamszus, Katrin, Schüller, Ulrich
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2020
Materias:
Biomarkers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650422/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.054
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