BIOM-57. PEDIATRIC TUMOR CLASSIFICATION THROUGH GENOME-WIDE METHYLATION PROFILING OF EXTRACELLULAR VESICLE DNA

BACKGROUND: Genome-wide methylation profiling reliably classifies pediatric central nervous system (CNS) tumors. Extracellular vesicles (EVs) are released by pediatric CNS tumor cells (pCC) and contain high molecular weight tumor DNA, rendering EVs a potential biomarker source to identify tumor subg...

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Publicat a:Neuro Oncol
Autors principals: Ricklefs, Franz, Maire, Cecile, Fita, Krys, Fritzsche, Friederike, Kammler, Gertrud, Westphal, Manfred, Lamszus, Katrin, Schüller, Ulrich
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Biomarkers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650422/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.054
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