CTIM-14. PELAREOREP AND GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR (GM-CSF) WITH STANDARD CHEMORADIOTHERAPY/ADJUVANT TEMOZOLOMIDE FOR GLIOBLASTOMA MULTIFORME (GBM) PATIENTS: REOGLIO PHASE I TRIAL RESULTS

BACKGROUND: Oncolytic viruses represent a novel treatment approach in GBM through oncolytic targeting as well as local immune activation. We designed a phase Ib, open-label study of intravenous reovirus (pelareorep) with GM-CSF alongside standard chemoradiotherapy to assess safety and tolerability....

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Main Authors: Kendall, Jessica, Chalmers, Anthony, McBain, Catherine, Melcher, Alan, Samson, Adel, Phillip, Rachel, Brown, Sarah, Short, Susan
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
Assuntos:
Clinical Trials: Immunologic
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650418/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.148
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