CSIG-13. TRPM7 INDUCES TUMORIGENESIS AND STEMNESS THROUGH NOTCH ACTIVATION IN GLIOMA

Our group found that the inhibitory effect of TRPM7 on proliferation and invasion of human glioma cell is mediated by multiple mechanisms. TRPM7 regulates miR-28-5p expression, which suppresses cell proliferation and invasion in glioma cells by targeting Ras-related protein Rap1b. In particular, our...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Wan, Jingwei, Guo, Alyssa, Liu, Mingli
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Cell Signaling and Signaling Pathways
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650375/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.125
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