Receptor-independent modulation of cAMP-dependent protein kinase and protein phosphatase signaling in cardiac myocytes by oxidizing agents

The contraction and relaxation of the heart is controlled by stimulation of the β1-adrenoreceptor (AR) signaling cascade, which leads to activation of cAMP-dependent protein kinase (PKA) and subsequent cardiac protein phosphorylation. Phosphorylation is counteracted by the main cardiac protein phosp...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Diering, Simon, Stathopoulou, Konstantina, Goetz, Mara, Rathjens, Laura, Harder, Sönke, Piasecki, Angelika, Raabe, Janice, Schulz, Steven, Brandt, Mona, Pflaumenbaum, Julia, Fuchs, Ulrike, Donzelli, Sonia, Sadayappan, Sakthivel, Nikolaev, Viacheslav O., Flenner, Frederik, Ehler, Elisabeth, Cuello, Friederike
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650233/
https://ncbi.nlm.nih.gov/pubmed/32868295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014467
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