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A Switch between Two Intrinsically Disordered Conformational Ensembles Modulates the Active Site of a Basic-Helix–Loop–Helix Transcription Factor
[Image: see text] We report a conformational switch between two distinct intrinsically disordered subensembles within the active site of a transcription factor. This switch highlights an evolutionary benefit conferred by the high plasticity of intrinsically disordered domains, namely, their potentia...
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| Publicat a: | J Phys Chem Lett |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Chemical
Society
2020
|
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7649839/ https://ncbi.nlm.nih.gov/pubmed/33030907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpclett.0c02242 |
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