Interferon-γ/Interleukin-27 Axis Induces Programmed Death Ligand 1 Expression in Monocyte-Derived Dendritic Cells and Restores Immune Tolerance in Central Nervous System Autoimmunity

Antigen (Ag)-specific tolerance induction by intravenous (i. v.) injection of high-dose auto-Ags has been explored for therapy of autoimmune diseases, including multiple sclerosis (MS). It is thought that the advantage of such Ag-specific therapy over non-specific immunomodulatory treatments would b...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Casella, Giacomo, Rasouli, Javad, Thome, Rodolfo, Descamps, Hélène C., Vattikonda, Asrita, Ishikawa, Larissa, Boehm, Alexandra, Hwang, Daniel, Zhang, Weifeng, Xiao, Dan, Park, Jeongho, Zhang, Guang-Xian, Alvarez, Jorge I., Rostami, Abdolmohamad, Ciric, Bogoljub
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7649367/
https://ncbi.nlm.nih.gov/pubmed/33193372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.576752
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